can i use prednsilone oral during one weekshe has pregnant for 5 month and asthma
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- Answered 4 Sep 2019 Conflict of interest declaration: None I’ve assumed you mean prednisolone (not prednsilone as stated in the question)! The UK’s NHS reports : “Prednisolone isn't usually recommended in pregnancy unless the potential benefits outweigh the risks. Prednisolone has occasionally been linked to problems in the first 12 weeks of pregnancy. High doses or long-term use can also affect the unborn baby's growth. If you take prednisolone in pregnancy, the baby's growth will be checked often.” They then link to BUMPs website, which states : “Is it safe to use systemic corticosteroids in pregnancy? There is no yes or no answer to this question as the requirement for a specific treatment varies from person to person and is dependent on factors such as the severity of the illness and the complications that could arise if treatment is altered or not given. When deciding whether to use systemic corticosteroids during pregnancy it is therefore important to weigh up how necessary they are to your health against any possible risks to you or your baby, some of which might depend on how many weeks pregnant you are.” We recommend you read the full article via the URL below. In 2017 “A Review of Systemic Corticosteroid Use in Pregnancy and the Risk of Select Pregnancy and Birth Outcomes.” was published , the abstract reports: “The evidence to date regarding corticosteroid exposure in pregnancy and select pregnancy and birth outcomes is limited and inconsistent. The authors provide a narrative review of published literature summarizing the findings for oral clefts, preterm birth, birth weight, preeclampsia, and gestational diabetes mellitus. Whenever possible, the results are limited to oral or systemic administration with a further focus on use in autoimmune disease. Although previous studies of corticosteroid exposure in pregnancy reported an increased risk of oral clefts in the offspring, more recent studies have not replicated these findings.” This is available as full free-text (URL below) Finally, you may want to look at the warning note on the drugs.com website  References 1) https://www.nhs.uk/medicines/prednisolone/ 2) http://www.medicinesinpregnancy.org/Medicine--pregnancy/Prednisolone/ 3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604866/ 4) https://www.drugs.com/pregnancy/prednisolone.html